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  • Trans-infection but not infection from within endosomal compartments after cell-to-cell HIV-1 transfer to CD4+ T cells

    Permanyer M, Ballana E, Badia R, Pauls E, Clotet B, Esté JA.

    IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, 08916 Badalona, Spain

    J Biol Chem. 2012 Sep 14;287(38):32017-26. doi: 10.1074/jbc.M112.343293. Epub 2012 Jul 30.

  • The origin of AIDS

    Miguel Angel Martínez. Fundació irsiCaixa, Hospital Universitari Germans Trias i Pujol, Badalona, Spain

  • Evolution of HIV-1 Protease over 14 Years: Fitness Loss or Robustness Gain?

    Elena Capel*, Glòria Martrus, Mariona Parera, Bonaventura Clotet and Miguel Angel Martínez. Irsicaixa AIDS Research Institute, University Hospital Germans Trias i Pujol of Badalona

  • Antiretroviral agents effectively block HIV replication after cell to cell transfer

    Marc Permanyer, Ester Ballana, Alba Ruiz, Roger Badia, Eva Riveira, Bonaventura Clotet and José A. Esté. Irsicaixa AIDS Research Institute, University Hospital Germans Trias i Pujol of Badalona

  • New nitrogen containing substituents at the indole-2-carboxamide yield high potent and broad spectrum indolylarylsulfone HIV-1 non-nucleoside reverse transcriptase inhibitors

    Giuseppe La Regina †, Antonio Coluccia †, Andrea Brancale ‡, Francesco Piscitelli †, Valeria Famiglini †, Sandro Cosconati II, Giovanni Maga #, Alberta Samuele #, Emmanuel Gonzalez ¥, Bonaventura Clotet ¥, Dominique Schols^, José A. Esté ¥, Ettore Novellino §, and Romano Silvestri †

    † Istituto Pasteur - Fondazione Cenci Bolognetti, Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza Università di Roma, Piazzale Aldo Moro 5, I-00185 Roma, Italy ‡ Welsh School of Pharmacy, Cardiff University, King Edward VII Avenue, Cardiff, CF10 3NB, U.K., Istituto di Chimica Biomolecolare, CNR, Piazzale Aldo Moro 5, I-00185 Roma, Italy # Institute of Molecular Genetics IGM-CNR, National Research Council, via Abbiategrasso 207, I-27100 Pavia, Italy ¥ IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Universitat Autonoma de Barcelona, 08916 Badalona, Spain ^ Rega Institute for Medical Research, Katholieke Universiteit Leuven, B-3000 Leuven, Belgium § Dipartimento di Chimica Farmaceutica e Tossicologica, Università di Napoli Federico II, Via Domenico Montesano 49, I-80131, Napoli, Italy
    II Dipartimento di Scienze Ambientali, Seconda Università di Napoli, Via Vivaldi 43, 81100 Caserta, Italy

    J Med Chem. 2012 Jul 26;55(14):6634-8. doi: 10.1021/jm300477h. Epub 2012 Jul 6