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  • Whole Genome Deep Sequencing of HIV-1 Reveals the Impact of Early Minor Variants Upon Immune Recognition During Acute Infection

    Matthew R. Henn1, Christian L. Boutwell2#, Patrick Charlebois1#, Niall J. Lennon1, Karen A. Power2, Alexander R. Macalalad1, Aaron M. Berlin1, Christine M. Malboeuf1, Elizabeth M. Ryan1, Sante Gnerre1, Michael C. Zody1, Rachel L. Erlich1, Lisa M. Green1, Andrew Berical2, Yaoyu Wang2, Monica Casali1, Hendrik Streeck2, Allyson K. Bloom2, Tim Dudek2, Damien Tully2, Ruchi Newman1, Karen L. Axten2, Adrianne D. Gladden2, Laura Battis2, Michael Kemper2, Qiandong Zeng1, Terrance P. Shea1, Sharvari Gujja1, Carmen Zedlack3, Olivier Gasser4, Christian Brander5,6, Christoph Hess4, Huldrych F. Günthard7, Zabrina L. Brumme2, Chanson J. Brumme2, Suzane Bazner8, Jenna Rychert8, Jake P. Tinsley9, Ken H. Mayer9, Eric Rosenberg8, Florencia Pereyra2, Joshua Z. Levin1, Sarah K. Young1, Heiko Jessen3, Marcus Altfeld2, Bruce W. Birren1, Bruce D. Walker2,10, Todd M. Allen2*

     

    1 Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, 2 Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America, 3 HIV Clinic Praxis. Jessen, Berlin, Germany, 4 Immunobiology Lab, Department of Biomedicine, University Hospital Basel, Basel, Switzerland, 5 Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain, 6 Irsicaixa AIDS Research Institute-HIVACAT, Hospital University Germans Trias I Pujol, Badalona, Spain, 7 Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Switzerland, 8 Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, 9 The Fenway Institute, Fenway Health, Boston, Massachusetts, United States of America, 10 Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America

     

    # These authors contributed equally to this work

    PLoS Pathog. 2012 Mar;8(3):e1002529. Epub 2012 Mar 8

  • In–Depth Characterization of Viral Isolates from Plasma and Cells Compared with Plasma Circulating Quasispecies in Early HIV-1 Infection

    Judith Dalmau1*, Francisco M. Codoñer1,2*, Itziar Erkizia1, Maria Pino1, Christian Pou1, Roger Paredes1,4, Bonaventura Clotet1,4, Javier Martinez-Picado1,3, Julia G. Prado1
    1AIDS Research Institute IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain, 2Lifesequencing, S.L., Parc Científic Universitat de València, Paterna, Valencia, Spain, 3Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain, 4Fundació Lluita contra la SIDA, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain

     

    * These authors contributed equally to this work

    PLoS One. 2012;7(2):e32714. Epub 2012 Feb 29

  • Rare LEDGF/p75 genetic variants in white long-term nonprogressor HIV+ individuals

    Ballana E1, Gonzalo E1, Grau E1, Iribarren JA2, Clotet B1, Este JA1

    1AIDS Research Institute IrsiCaixa, Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona 2Unidad de Enfermedades Infecciosas, Hospital Donostia, Po. Dr. Begiristain, s/n 20014 San Sebastián, Spain

    AIDS. 2012 Feb 20;26(4):527-8

  • Differential prevalence of the HLA-C -35 CC genotype among viremic long term non-progressor and elite controller HIV+ individuals

    Ester Ballanaa, 1, Alba Ruiz-de Andresa, 1, Beatriz Mothea, b, Eva Ramirez de Arellanoc, Francisco Aguilarc, Roger Badiaa, Eulalia Graua, Bonaventura Cloteta, Margarita del Valc, d, Christian Brandera, e, José A. Estéa
    a IrsiCaixa-HIVACAT, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain b Lluita Contra la SIDA Foundation, Hospital Universitari Germans Trias i Pujol, Badalona, Spain c Unidad de Inmunología Viral, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain d Centro de Biología Molecular Severo Ochoa (CSIC-UAM), Madrid, Spain e Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain

     

    1 Both authors contributed equally to this work

    Immunobiology. 2012 Jan 8

  • Check-ear cohort: a community and researchers collaboration for STIs screening in HIV negative MSM

    Pep Coll, Eduardo Ditzel, Agathe Leon, Ferran Pujol, Michael Meulbroek, Jordi Casabona, Emma Fernandez, Isabel Bravo, Jorge Saz, Hector Taboada, Laia Ferrer, Josep Maria Gatell, Bonaventura Clotet, Christian Brander.