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Some of the Latest
News Concerning the FundaciÑ irsiCaixa
and the Worldwide HIV/AIDS Epidemic.
| Seminar "Perspectives on the genetic analysis of susceptibility in infectious diseases: possibilities and pitfalls" |
2008-02-28
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JaumeBertranpetit
BiologiaEvolutiva, CEXS
UniversitatPompeuFabra
PRBB (Barcelona BiomedicalResearchPark)
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monday March 3, 2008
12:00h Room 5, School of Medicine
Hospital Universitari Germans Triasi Pujol
Camí de les Escoles s/n
Badalona
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Work Position
Retrovirology Laboratory
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2008-01-30
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| A position is available within the Service Department of high performance liquid chromatography –HPLC- area.
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A position is available within the Service Department of high performance liquid chromatography –HPLC- area. The work focuses on the routine therapeutic drug monitoring and pharmacokinetics studies of current and new antiretroviral drugs against Human Immunodeficiency Virus (HIV-1) infection. We require a technician specialist or analytical chemistry, pharmacologist or pharmacist. Preference will be given to candidates experienced in HPLC analysis.
Review of applications will begin immediately and continue until this position is filled.
Qualified candidates should submit a letter of application with statement of research interest as well as resume and copy of academic file to:
Dra. Lidia Ruiz Tabuenca. irsiCaixa Foundation. University Hospital Germans Trias i Pujol. 08916 Badalona, Barcelona. SPAIN, e-mail lruiz@irsicaixa.es clearly indicating “Work Position” in the subject line.
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| http://www.irsicaixa.org/english/news/n_job.php3 |
| FPI Fellowship Grant in Biomedicine |
2007-12-12
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| Pathogenesis of the Human Immunodeficiency Virus (HIV-1) and AIDS: molecular and cell biology.
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Offer We offer the possibility of applying for a fellowship grant FPI linked to the project “Mature dendritic cells enhance HIV-1 transmission to CD4+ T-cells: molecular mechanisms and implications for viral pathogenesis“ (SAF2007-64696) funded by the Plan Nacional R+D. This grant with last for 2 years and can be extended 2 more years after obtaining the master degree.
Field Pathogenesis of the Human Immunodeficiency Virus (HIV-1) and AIDS: molecular and cell biology.
Candidates profile Graduates in Biology, Biochemistry, biotechnology, Pharmacy, Chemistry or Medicine. Full time dedication during the project will be required. Preference will be given to candidates experienced in molecular and cell biology and/or protein biochemistry. Candidates with academic files containing marks greater than 2 are encouraged.
Deadline Review of applications will begin immediately and continue until this position is filled. The basis of the application will be announced shortly in the web site of the Ministry of Education and Science (MEC).
Contact Qualified candidates should submit a letter of application with statement of research interest as well as resume, copy of academic file and at least one letter of recommendation to: Dr. Javier Martinez-Picado irsiCaixa Foundation. University Hospital Germans Trias i Pujol. 08916 Badalona, Barcelona. SPAIN. E-mail: jmpicado@irsicaixa.es (indicate “FPI Grant” in the subject line)
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| http://www.irsicaixa.org/english/news/n_job.php3 |
| Simposium irsiCaixa/HIVACAT 2007 |
2007-11-15
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Barcelona, 23 November 2007
CosmoCaixa: Teodor Roviralta, 47-51, Barcelona
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Our goal is to bring leading experts on AIDS together to discuss the latest news on HIV research, including vaccines and new treatments:
9:00 Welcome and Reception.
Chairman: Ch. Boucher, J.M. Gatell and B. Clotet
9:30 Moderador: J.M. Gatell / B. Clotet
> 09:30 - 10:00. Ch. Boucher
“Novel mechanism for boosted PI resistance”
> 10:00 - 10:30. J. Schapiro
“New targets, new drugs and new strategies:
CCR5, RAL, DRV, Etravirine”
> 10:30 - 11:00. Discussion
11:00 - 11:30 > Café
11:30 Moderador: B. Clotet / J.M. Gatell
> 11:30 - 12:00. B. Autran
“HIV Therapeutic Vaccines”
> 12:00 - 12:30. A. Telenti
“HIV Host genetics”
> 12:30 - 13:00. C. Brander
“New vaccine development”
> 13:00 - 13:30. M. Stevenson
“HIV Eradication, is it possible?”
> 13:30 - 14:00. Discussion |
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| 1st Workshop on HIV Immunology |
2007-06-06
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| Badalona, June 8th 2007
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The workshop is organized by HIVACAT, Programa Català d’investigació i Desenvolupament de Vacunes per la SIDA,
Hospital Germans Trias i Pujol (Fundació irsiCaixa) and
Hospital Clínic (Fundació Clínic)
The workshop will be held at the Hospital Universitari Germans Trias i Pujol
Aula Polivalent
Edifici de Recerca IGTP Ctra. de Can Ruti, Camí de les Escoles
Contact Cecilia Alcaraz 93-4656374 |
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| Workshop "Immunogens for HIV vaccine and dendritic cells" |
2006-12-17
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Hospital Clínic, Barcelona
December 18, 2006
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9.00 h. Welcome.
Joan Rodes. General Manager. Hospital Clínic. Barcelona
José M Gatell. Hospital Clínic. Barcelona. Spain
Bonaventura Clotet. Hospital Germans Trias I Pujol. IRSICAIXA, Badalona.
9.10 h. Objective of the meeting.
Felipe García. Hospital Clínic. Barcelona. Spain
FIRST PART: DENDRITIC CELLS MODEL
9.20 h. An ex vivo model to investigate the interaction of HIV immunogens with dendritic cells and their capacity to induce HIV-specific immune responses in autologous T-cells from non-advanced HIV-infected patients
Teresa Gallart. Hospital Clínic. Barcelona. Spain
9. 40 h. A model for first screening of HIV immunogens in vitro using simplest cellular assays.
Montserrat Plana. Hospital Clínic. Barcelona. Spain
10. 00 h. Influence of mode of administration and the choice of adyuvants in animal model of vaccination. Relevance of targeting of vaccines toward DC.
Behazine Combadiere. Université Pierre et Marie Curie. Paris. France
10.20 h. Evaluation of vaccine efficacy in macaques against mucosal challenge.
Roger Le Grand. Service of Neurovirology. Medical Research Department. Life Science Direction of the French Atomic Energy Commission (CEA). Paris. France
10. 40 h. DC maduration and HIV transmission. Relevance for a MDDC based therapeutic vaccination.
Javier Martínez-Picado. Hospital Germans Trias I Pujol. IRSICAIXA, Badalona. Spain
11.00 h. Break coffee
SECOND PART: HIV IMMUNOGENS TO BE USED TO PULSE MDDC
Autologous or recombinant vector of HIV
11.30 h. Heat inactivated autologous HIV.
Cristina Gil. Hospital Clinic, Barcelona, Spain.
11. 45 h. AT-2 inactivated autologous HIV.
Jeff Lifson. National Cancer Institute, Frederick, USA.
12. 00 h. Infectious but non-replicative HIV virions by deletion of reverse transcriptase gene (RT) in NL.4.3 strain (NL-4.3-RT), and other NL-4.3-RT)-derived recombinant chimeric virions that will bear the HIV genes of patients (gag, nef, env) as well as chimeric and pseudotyped virions with the envelope of VSV-G
José Alcamí. Instituto de Salud Carlos III, Madrid, Spain.
Sonsoles Sánchez. Hospital Clínic, Barcelona, Spain.
Virus and Bacterial vectors
12.15 h. Modified Pox virus, strain MVA clade -B (expressing HIV-1 Bx08gp120 and IIIB gagpolnef)
Mariano Esteban. Centro Nacional de Biotecnología, Madrid. Spain.
12. 30 h. BCG recombinant, expressing HIV-1 gag, pol y env subtipo B
Joan Joseph. Hospital Clínic, Barcelona, Spain.
Nanoparticles and dendrimers
12.45 h. Biodegradable synthetic colloidal carrier made of poly-lactic acid (PLA) nanoparticles covered with adsorbed antigens.
Bernard Verrier. INSERM. Lyon. France
13. 00 h. “Pseudovirus” consisting of carbosilane dendrímers conjugated to peptides of the main components of HIV
María Angeles Muñoz. Hospital Gregorio Marañon, Madrid. Spain.
13. 15 h. Multivalent peptido-glycodendritic systems expressing HIV antigens.
Rafael Delgado. Hospital 12 de Octubre, Madrid. Spain.
13. 30 h LUNCH
15. 00 h – 16. 30 h. THIRD PART:
Teresa Gallart. Discussion and schedule of testing of immunogens in “in vitro” models.
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| Presentation of the "Centre Català d'Investigació i Desenvolupament de vacunes per a la sida (HIVACAT)" Catalan Center for AIDS Vaccine Research Development |
2006-09-02
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| The Catalan Ministries of Health, Education and Universities, The Obra Social of "Caixa" and the IDIBAPS-Fundació Clínic contributed to the creation of this new center
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| http://www.gencat.net/salut/depsan/units/sanitat/html/ca/premsa/doc11114.html |
| The international consortium EuroCHAVI will study the genetics of HIV immune response |
2006-06-22
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| A pioneer collaboration between USA, Europe and Austràlia
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| The project is aimed to identify genetic differences involved in the immune resposne to HIV infection. The Hospitals Clínic and Germans Trias i Pujol from Barcelona are the Spanish centers that will participate in this study, that will be coordinated by the Duke University and funded by the NIH. |
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| Research Award |
2006-06-19
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| The NEW AIDS most highly cited authors
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The NEW AIDS most highly cited author award 2006 for the Clinical Science section of the journal. This award recognises authors of the most highly cited scientific paper of 2004 published in AIDS over the period 2002 to 2003 (based on data analysis from Thomson Scientific (formerly ISI) Journal Citation Reports® data) and will be awarded at the XVIth International AIDS Conference, 13 - 18 August 2006, Toronto, Canada. This will become an annual award to recognise excellence in research published in this journal.
The most highly cited paper is:
Clinical utility of HIV-1 genotyping and expert advice: the Havana trial
published in AIDS vol 16, issue 2, pp 209-218, January 25, 2002.
The award will comprise of a certificate signed by the Editor-in-Chief Jay Levy, as well as the other Editors; Brigitte Autran, Roel Coutinho and John Phair and a cheque for USD$500
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| The Fundació irsiCaixa commemorates its tenth anniversary. |
2006-02-03
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| What we did during the last 10 years?
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We have prepared a brief presentation of our main activities, not only scientific but also educational and informative.
We also wish to show you the new challenges of the Fundació irsiCaixa in the near future.
You will find all this information by following the link "irsiCaixa 10 years of research on HIV/AIDS” located in our homepage. |
| http://www.irsicaixa.org/catalan/index.php3# |
| SEMINAR, March 8, 2006 (12:00): RNA interference gene therapy for AIDS patients |
2006-01-31
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Prof. Dr. Ben Berkhout
Department of Human Retrovirology, University of Amsterdam, Academic Medical Center, The Netherlands
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Room 1 (Library)
Hospital Universitari Germans Trias i Pujol, Ctra del Canyet s/n, Badalona
How to arrive? |
| http://www.irsicaixa.org/catalan/about/a_maps.html |
| UNAIDS/WHO AIDS Epidemic Update 2005 report launched |
2005-12-02
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| HIV INFECTION RATES DECREASING IN SEVERAL COUNTRIES BUT GLOBAL NUMBER OF PEOPLE LIVING WITH HIV CONTINUES TO RISE
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| There were an additional five million new infections in 2005. The number of people living with HIV globally has reached its highest level with an estimated 40.3 million people, up from an estimated 37.5 million in 2003. More than three million people died of AIDS-related illnesses in 2005; of these, more than 500000 were children |
| http://www.unaids.org/en/default.asp |
Guerau Fernàndez Isern, PhD Dissertation:
"High Resolution of the Genetic and Phenotypic Structure of the HIV-1 quasispecies"
(December 1, 12:30 am) |
2005-11-22
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| Defense of the PhD Dissertation by Guerau Fernàndez Isern on December 1 (12:30 am) at the Dissertation room of the new School of Medicine - University Hospital Germans Trias i Pujol. |
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| V International Workshop on HIV Eradication 11/11/05 |
2005-11-02
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| Open to all attendees. Registration is free (please contact CAlcaraz@irsicaixa.es)
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Program:
· Dr. Douglas Richman
University of California San Diego (UCSD), La Jolla, EEUU
· Dr. Giuseppe Pantaleo
Centre Hospitalier Universitaire Vaudois, Lausanne, Suiza
· Dr. Jonathan Schapiro
Stanford University, San Francisco, EEUU
· Dr. Daniel Kuritzkes
Brigham and Women’s Hospital, Cambridge, Massachusetts, EEUU
· Dr. Amalio Telenti
Centre Hospitalier Universitaire Vaudois, Lausanne, Suiza
· Dr. Luis Menéndez-Arias
Centro de Biología Molecular Severo Ochoa, Madrid
· Dr. Jan Van Lunzen
Medizinische Kernklinik, Univerdad de Hamburgo, Alemania
· Dr. Charles Boucher
Utrecht University, Utrech, Holanda
· Dr. Franco Lori
Research Institute for Genetic and Human Therapy, Washington, EEU / Pavia, Italia
· Dra. Brigitte Autran
Groupe Hospitalier Pitié-Salpêtriere, París, France
· Dr. Pedro Cahn
Presidente de la “International AIDS Society”
· Dr. José A Esté
· Dr. Miguel Ángel Martínez
· Dra. Lidia Ruiz
· Dra. Margarita Bofill
· Dr. Julià Blanco
· Dr. Javier Martínez-Picado
Fundació irsiCaixa
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Julia García Prado PhD Dissertation:
"HIV-1 Fitness Variations during Antiretroviral Therapy"
(September 26, 12 am) |
2005-09-14
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| Defense of the PhD Dissertation by Julia García Prado on September 26 (12 am) at the Dissertation room of the new School of Medicine - University Hospital Germans Trias i Pujol. |
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| New cases of AIDS in Spain (2004) |
2005-08-25
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| The Spanish Ministry of Health considers a total of 2,071 new cases of AIDS in 2004, 6.6% less than in 2003. A 45.7% of these new cases were due to sexual HIV transmission
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AIDS cases associated to the shared use of syringes between drug users has diminished, but those due to sexual transmission remain stable. Among new AIDS patients that ignored its condition of HIV carriers, a 57.7% contracted the infection by sexual route
The early diagnosis of the infection by HIV is key to reduce the incidence of AIDS. For this reason, the Spanish Ministry of Health recommends to the people who had unsafe sex with new or occasional partners, as well as to the pregnant women, to test HIV seroconversion.
Since the extension of the new antiretrovirals treatments at the end of 1996, AIDS incidence has diminished a 69%, although Spain is still one of the more affected countries of Western Europe
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| http://cne.isciii.es/htdocs/sida/sidavih.htm |
| New UNAIDS report unveils latest global epidemic trends |
2004-07-07
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| 1.1 million people infected with HIV in Asia last year alone
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UNAIDS warned that the number of people living with HIV, the virus
that causes AIDS, has risen in every region of the world and last year five million people
became newly infected with HIV -- more people than any previous year.
These findings are contained in the 2004 UNAIDS Report of the global AIDS epidemic,
released today in advance of the XV International AIDS Conference, to be held in Bangkok
from 11-16 July 2004. The new report represents the most accurate picture of AIDS to date
due to the more comprehensive country surveillance data and improved methods for
estimating HIV rates.
“Despite increased funding, political commitment and progress in expanding access to HIV
treatment over the past two years, the AIDS epidemic continues to outpace the global
response, “ said Dr Peter Piot, UNAIDS Executive Director, at the press launch of the report.
Since the 2002 AIDS Conference in Barcelona, more than nine million people have become
infected and six million have died of AIDS. “These numbers demonstrate the enormity of the
challenge in both preventing millions of infections and treating those living with HIV,” added
Dr Piot. “Until we recognize AIDS as the development and security issue of our time, we will
not succeed in beating the epidemic.”
The number of people living with HIV continues to grow – from 35 million in 2001 to 38
million in 2003. The 2004 UNAIDS report highlights the latest global trends and, for the first
time, features revised HIV prevalence rates for previous years, allowing for a better
understanding of how the epidemic is spreading.
For the first time, the report compares new estimates for 2003 with revised estimates for
2001 based on improved methodologies. This is the best way we know how to obtain a more
accurate picture of the AIDS epidemic. Although the new global estimates are slightly lower
than the previously published estimates, the actual number of people living with HIV has not
decreased; rather the epidemic continues to grow based on revised 2001 estimates.
“There is no time to misread the signals, with Asia facing life and death choices in preventing
a full-blown AIDS catastrophe in the region,” said Dr Piot. “Equally alarming, infections in
Africa continue to increase and people are dying in large numbers.” |
| http://www.unaids.org/en/default.asp |
| XV International AIDS Conference |
2004-07-07
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| Bangkok 11-16 July 2004
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The Conference will feature a unified program with abstract-driven and non-abstract driven sessions. The abstract program will comprise of 5 tracks:
Track A: Basic Science
Track B: Clinical Research, Treatment and Care
Track C: Epidemiology and Prevention
Track D: Social and Economic Issues
Track E: Policy and Program Implementation
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| http://www.aids2004.org |
| The irsiCaixa Foundation is participating in the educational project "SIDA Saber Ajuda" |
2003-12-17
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| The irsiCaixa Foundation is participating in the educational project "SIDA Saber Ajuda" throught the publication of summary articles related to AIDS and its etiological agent the HIV. |
| http://www.sidasaberajuda.com/nouc/index.html |
| Structured interruption of treatment did not confer immunologic or virologic benefits in patients infected with multidrug-resistant HIV |
2003-10-02
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| Published in The Journal of Infectious Diseases vol 188 pages 977-985(October 2003)
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| We evaluated the efficacy of a 5-drug salvage regimen, preceded by a 12-week, structured treatment interruption (STI), in 46 multidrug-treated, human immunodeficiency virus type 1–infected patients with detectable viremia. Patients were randomly assigned to receive a 5-drug salvage regimen immediately or after 12 weeks of STI. No differences in CD4 cell counts were seen between groups at week 48. A complete reversion to wild-type genotype was detected in 35% of patients in the interuption group, but this phenomenon did not affect the virological response. The only overall baseline factor associated with ensuing virus suppression was a lower number of nucleoside reverse-transcriptase inhibitor–resistant mutations. A prior STI seems to confer no additional benefit to subsequent virological or immunological outcomes of a salvage regimen. |
| http://www.irsicaixa.org/english/research/abstract.php3?codigo=249 |
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