CONTENIDO

  • Changes in codon-pair bias of human immunodeficiency virus type 1 have profound effects on virus replication in cell culture

    Gloria Martrus, Maria Nevot, Cristina Andres, Bonaventura Clotet and Miguel Angel Martinez

     

    Fundació IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona (UAB), Badalona 08916, Spain

     

    doi: 10.1186/1742-4690-10-78

  • Identification of Hck Inhibitors As Hits for the Development of Antileukemia and Anti-HIV Agents

    Dr. Cristina Tintori1, Ilaria Laurenzana2, Francesco La Rocca2, Dr. Federico Falchi1,3, Prof. Fabio Carraro4, Alba Ruiz5, Prof. José A. Esté5, Miroslava Kissova6, Dr. Emmanuele Crespan6, Prof. Giovanni Maga6, Prof. Mariangela Biava7, Dr. Chiara Brullo8, Prof. Silvia Schenone8, Prof. Maurizio Botta1,9,*

     

    1Dipartimento Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena, Via A. De Gasperi 2, 53100 Siena (Italy) 2IRCCS-Centro di Riferimento Oncologico Basilicata (CROB), Laboratory of Preclinical and Translational Research, Via Padre Pio 1, Rionero in Vulture 85028 Potenza (Italy) 3Department of Pharmacy and Biotechnology, Alma Mater Studiorum, Università di Bologna, Via Belmeloro 6, 40126 Bologna (Italy) 4Dipartimento di Medicina Molecolare e dello Sviluppo, Università degli Studi di Siena, Via A. De Gasperi 2, 53100 Siena (Italy) 5Irsicaixa, Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona, 08916 Badalona (Spain) 6Istituto di Genetica Molecolare, IGM-CNR, Via Abbiategrasso 207, 27100 Pavia (Italy) 7Dipartimento di Chimica e Tecnologie del Farmaco, Università La Sapienza, Piazzale Aldo Moro 5, 00185 Roma (Italy) 8Dipartimento di Scienze Farmaceutiche, University of Genoa, Viale Benedetto XV 3, 16132 Genova (Italy) 9Biotechnology College of Science and Technology, Temple University, Biolife Science Building, Suite 333, 1900 North 12th Street, Philadelphia, PA 19122 (USA)

    doi: 10.1002/cmdc.201300204

  • Significant changes in integrase-associated HIV-1 replication capacity between early and late isolates

    Elena Capel, Mariona Parera, Bonaventura Clotet, Miguel Ángel Martínez


    Fundació IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Badalona 08916, Spain

    doi: 10.1016/j.virol.2013.06.023. Epub 2013 Jul 21

  • Impact of Antiretroviral Drugs in Pregnant Women and Their Children in Africa: HIV Resistance and Treatment Outcomes

    Roger Paredes1,2,3, Vincent C. Marconi4,5,6, Shahin Lockman7,8,9, Elaine J. Abrams10,11 and Louise Kuhn10,12

     

    1IrsiCaixa AIDS Research Institute 2HIV Unit, Internal Medicine Department, Hospital Universitari Germans Trias i Pujol 3Universitat Autònoma de Barcelona, Barcelona, Catalonia, Spain 4Division of Infectious Diseases, Emory University School of Medicine 5Department of Global Health, Rollins School of Public Health, Emory University 6Atlanta Veterans Affairs Medical Center, Atlanta, Georgia 7Brigham and Women's Hospital 8Harvard School of Public Health, Boston, Massachusetts 9Botswana Harvard School of Public Health AIDS Initiative Partnership, Gaborone, Botswana 10Department of Epidemiology, Mailman School of Public Health, Columbia University 11Department of Pediatrics, College of Physicians & Surgeons, Columbia University 12Gertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York

    doi: 10.1093/infdis/jit110

  • Early but limited effects of raltegravir intensification on CD4 T cell reconstitution in HIV-infected patients with an immunodiscordant response to antiretroviral therapy

    Eugènia Negredo1, Marta Massanella2, Maria C. Puertas2, Maria J. Buzón2, Jordi Puig1, Núria Pérez-Alvárez1,3, Josué Pérez-Santiago4, Anna Bonjoch1, José Moltó1, Antoni Jou1, Patricia Echeverría1, Josep M. Llibre1, Javier Martínez-Picado2,5, Bonaventura Clotet1,2 and Julià Blanco2

     

    1Lluita contra la SIDA foundation, Institut de Recerca en Ciències de la Salut Germans Trias i Pujol (IGTP), Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Barcelona, Catalonia, Spain 2IrsiCaixa-HIVACAT, Institut de Recerca en Ciències de la Salut Germans Trias i Pujol (IGTP), Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Barcelona, Catalonia, Spain 3Statistics and Operation Research Department, Technical University of Catalonia, Barcelona, Spain 4University of California San Diego, San Diego, California, USA 5Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain

    doi: 10.1093/jac/dkt183