IrsiCaixa

Mark A. Brockman^a,^b, Denis R. Chopera^a, Alex Olvera^c, Chanson J. Brumme^b,^d, Jennifer Sela^e, Tristan J. Markle^a, Eric Martin^a, Jonathan M. Carlson^f, Anh Q. Le^a, Rachel McGovern^b, Peter K. Cheung^b, Anthony D. Kelleher^g, Heiko Jessen^h, Martin Markowitzⁱ, Eric Rosenberg^j, Nicole Frahm^k, Jorge Sanchez^l, Simon Mallal^m, Mina John^m, P. Richard Harrigan^b, David Heckerman^f, Christian Brander^c,ⁿ, Bruce D. Walker^e and Zabrina L. Brumme ^a,^b

^aSimon Fraser University, Burnaby, Canada ^bBritish Columbia Centre for Excellence in HIV/AIDS, Vancouver, Canada ^cAIDS Research Institute irsiCaixa, Badalona, Spain ^dUniversity of British Columbia, Vancouver, Canada ^eRagon Institute of MGH, MIT, and Harvard, Boston, Massachusetts, USA  ^fMicrosoft Research, Los Angeles, California, USA ^gKirby Institute, University of New South Wales, Sydney, Australia ^hJessen Praxis, Berlin, Germany ⁱAaron Diamond AIDS Research Center, New York, New York, USA  ^jMassachusetts General Hospital, Boston, Massachusetts, USA ^kFred Hutchinson Cancer Research Center, Seattle, Washington, USA ^lAsociación Civil IMPACTA Salud y Educacion, Lima, Peru ^mMurdoch University, Perth, Australia ⁿInstitució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain

Matthew R. Henn¹, Christian L. Boutwell^2#, Patrick Charlebois^1#, Niall J. Lennon¹, Karen A. Power², Alexander R. Macalalad¹, Aaron M. Berlin¹, Christine M. Malboeuf¹, Elizabeth M. Ryan¹, Sante Gnerre¹, Michael C. Zody¹, Rachel L. Erlich¹, Lisa M. Green¹, Andrew Berical², Yaoyu Wang², Monica Casali¹, Hendrik Streeck², Allyson K. Bloom², Tim Dudek², Damien Tully², Ruchi Newman¹, Karen L. Axten², Adrianne D. Gladden², Laura Battis², Michael Kemper², Qiandong Zeng¹, Terrance P. Shea¹, Sharvari Gujja¹, Carmen Zedlack³, Olivier Gasser⁴, Christian Brander⁵,⁶, Christoph Hess⁴, Huldrych F. Günthard⁷, Zabrina L. Brumme², Chanson J. Brumme², Suzane Bazner⁸, Jenna Rychert⁸, Jake P. Tinsley⁹, Ken H. Mayer⁹, Eric Rosenberg⁸, Florencia Pereyra², Joshua Z. Levin¹, Sarah K. Young¹, Heiko Jessen³, Marcus Altfeld², Bruce W. Birren¹, Bruce D. Walker²,¹⁰, Todd M. Allen^2*

¹ Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, ² Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, United States of America, ³ HIV Clinic Praxis. Jessen, Berlin, Germany, ⁴ Immunobiology Lab, Department of Biomedicine, University Hospital Basel, Basel, Switzerland, ⁵ Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain, ⁶ Irsicaixa AIDS Research Institute-HIVACAT, Hospital University Germans Trias I Pujol, Badalona, Spain, ⁷ Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Switzerland, ⁸ Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, ⁹ The Fenway Institute, Fenway Health, Boston, Massachusetts, United States of America, ¹⁰ Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America

^# These authors contributed equally to this work